Once we learned how to create solution configurations, project configurations and project platforms, and the lack of support to create new solution platforms, the next thing is to be able to change the project configuration for a given solution configuration. Alas, this is possible in VS 2005 and 2012 but VS 2008 and 2010 have a bug that ruins the attempt:

HOWTO: Change the build configuration of a project from a Visual Studio add-in
http://www.mztools.com/articles/2013/MZ2013012.aspx

BUG: Build configuration of a project cannot be changed from a Visual Studio add-in
http://www.mztools.com/articles/2013/MZ2013013.aspx